Table 3.
Effects of Artemisinin (20 μmol/L) on the High K+ Solution Induced Contraction (mg/mm) in MA, CA and PA in WKYs and SHRs
WKY | SHR | |||||
---|---|---|---|---|---|---|
Saline | 0.1%DMSO | Artemisinin | Saline | 0.1%DMSO | Artemisinin | |
MA | 258.2 ± 19.8 | 271.3 ± 23.1 | 266.4 ± 26.4 | 665.5 ± 28.6† | 674.2 ± 25.1† | 669.7 ± 31.4† |
CA | 157.5 ± 9.8 | 161.5 ± 36.2 | 168.2 ± 28.7 | 295.6 ± 25.5† | 305.7 ± 30.2† | 290.0 ± 26.7† |
PA | 203.5 ± 20.4 | 199.3 ± 11.9 | 223.1 ± 21.0 | 346.7 ± 20.4† | 339.6 ± 26.9† | 323.0 ± 20.2† |
Notes: Values are expressed as mean ± SE. *P<0.05 vs Saline or 0.1%DMSO. †P<0.05 vs WKYs. n=6 for each group.