Table 2.
Lean | Obese | |||
---|---|---|---|---|
Insulin sensitive | Quartile 2 | Insulin resistant | ||
Abdominal SAT perfusion (mL/kg tissue/min) | 33 (24, 56) | 15 (11, 28)* | 18 (2, 57)* | 14 (4, 25)* |
Abdominal SAT oxygenation (mmHg) | 58 (52, 67) | 49 (45, 53)* | 50 (47, 58)* | 49 (45, 56)* |
Thigh SAT perfusion (mL/kg tissue/min) | 9 (7, 18)† | 10 (8, 13) | 12 (10, 15) | 8 (7, 11) |
Data are median (IQR). Perfusion was assessed during the hyperinsulinemic-euglycemic clamp at the same time as adipose tissue glucose uptake was assessed. ANOVA was used to evaluate differences in outcome variables among groups. Data were log transformed to achieve normal distribution before analysis.
Significant main effect of obesity (P < 0.05).
Significantly different from abdomen (P < 0.05).