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. 2021 Aug 3;70(10):2264–2274. doi: 10.2337/db21-0126

Figure 5.

Figure 5

Effects of chronic ICV leptin infusion on mRNA expression of GK, PEPCK, and LPL and key proteins involved in glucose and fatty acid oxidation in livers of parabiotic rats. Quantitative RT-PCR analysis of GK (A), PEPCK (B), and LPL (C) mRNA expression in liver samples. Protein expression of p-ACC/ACC (D), p-PDH/PDH (E), PPARγ (F), and FBP1 (G) (in liver from diabetic ICV vehicle-treated only, leptin, or vehicle-conjoined treated rats. *P < 0.05 compared with diabetic Veh-Veh group using one-way ANOVA. A.U., arbitrary units.