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. 2021 Jul 21;6(11):1–9. doi: 10.1001/jamacardio.2021.2537

Table 1. Perinatal and Current Baseline Characteristics of the Study Population.

Characteristic No. (%) of group participants P value
Control (n = 77) Born SGA (n = 81)
Perinatal characteristic
Birth weight, median (IQR), g 3380 (3250-3550) 2570 (2440-2700) NA
Gestational age at delivery, median (IQR), wk 40 (39-40) 40 (39-41) .06
Birth weight centile, median (IQR) 53 (40-66) 1 (1-3) NA
Prematurity 2 (3) 0 (0) .14
Gestational hypertension 1 (1) 6 (7) .06
Breastfeedinga 9 (12) 17 (21) .12
Current baseline characteristic
Age, median (IQR), y 33.7 (31.0-37.1) 34.4 (30.8-36.7) .96
Sex
Female 33 (43) 43 (53) .20
Male 44 (57) 38 (47)
White ethnicity 77 (100) 81 (100) NA
Height, median (IQR), m2 1.7 (1.7-1.8) 1.7 (1.6-1.7) <.001
Weight, median (IQR), kg 73.3 (60.9-85.0) 70.0 (57.7-79.1) .07
BMI, median (IQR) 24.3 (21.4-26.6) 24.7 (21.7-28.4) .48
Body surface area, median (IQR), m2b 1.9 (1.7-2.0) 1.8 (1.6-1.9) .001
Previous familiar history of myocardial infarction 10 (13) 7 (9) .37
Educational level
Primary 9 (12) 8 (10) .049
Secondary 3 (4) 7 (9)
Postsecondary nontertiary 10 (13) 20 (26)
Short-cycle tertiary 7 (9) 13 (16)
University 48 (62) 33 (41)
Smoking habit 42 (57) 42 (52) .67
Overweightc 33 (43) 35 (43) .96
Sedentary time, median (IQR), h 90.5 (76.5-106.0) 87.0 (73.0-105.0) .24
Level of physical activityd
Low 35 (48) 33 (43) .25
Moderate 26 (36) 22 (29)
High 12 (16) 21 (28)
Diabetes 0 (0) 3 (4) .38
Asthma 4 (5) 9 (11) .18
Chronic hypertension 2 (3) 2 (2) .96
Blood pressure, median (IQR), mm Hge
Systolic 118.7 (110.2-128.7) 117.5 (109.2-126.7) .84
Diastolic 71.5 (66.7-78.2) 72.0 (63.7-80.2) .90
Glucose level, median (IQR), mg/dL 89 (83-97) 89 (81-96) .31
Cholesterol level, median (IQR), mg/dL
LDL 109 (95-134) 111 (101-125) .98
HDL 46 (35-57) 47 (39-54) .47
Triglyceride, median (IQR), mg/dL 105 (76-150) 86 (69-123) .10

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); HDL, high-density lipoprotein; IQR, interquartile range; LDL, low-density lipoprotein; NA, nonapplicable; SGA, small for gestational age.

SI conversion factors: To convert glucose to mmol/L, multiply by 0.0555; LDL and HDL to mmol/L, multiply by 0.0259; and triglyceride to mmol/L, multiply by 0.0113.

a

Breastfeeding considered present if existed (exclusive or mixed) at any duration.

b

Body surface area calculated using the Haycock formula.

c

Overweight defined as BMI above 25.

d

Basal level of physical activity assessed by the International Physical Activity Questionnaire.16

e

Blood pressure was obtained at the beginning of the medical evaluation by a trained nurse while the participant was seated after having rested for 5 to 10 minutes.