Table 2. Cardiac Magnetic Resonance Results for the Study Populations.
Measure | Median (IQR) | P value | Adjusted P valuea | |
---|---|---|---|---|
Control (n = 77) | Born SGA (n = 81) | |||
Left morphometry b | ||||
LVEDV, mean (SD), mL/m2 | 86.6 (12.8) | 83.4 (12.2) | .10 | .27 |
LVESV, mean (SD), mL/m2 | 34.5 (7.2) | 34.3 (6.5) | .91 | .49 |
LV base-to-apex length, mm/m2 | 5.0 (4.7-5.3) | 5.0 (4.7-5.5) | .11 | .53 |
LV basal diameter, mm/m2 | 25.6 (23.8-27.0) | 25.9 (24.1-27.1) | .29 | .72 |
LV sphericity index, mean (SD)c | 0.4 (0.1) | 0.4 (0.1) | .98 | .62 |
Relative wall thicknessd | 2.3 (2.0-2.5) | 2.2 (1.9-2.6) | .63 | .62 |
LV mass, mean (SD), g/m2 | 47.8 (11.9) | 45.4 (8.8) | .25 | .64 |
Left atrial area, cm2/m2 | 12.6 (11.7-13.7) | 12.3 (10.9-14.3) | .50 | .29 |
Aortic area, mean (SD), cm2/m2 | 3.6 (0.6) | 3.7 (0.7) | .26 | .66 |
Right morphometry b | ||||
RVEDV, mean (SD), mL/m2 | 78.8 (15.1) | 74.1 (13.8) | .04 | .13 |
RVESV, mL/m2 | 34.4 (28.3-42.9) | 32.1 (27-36.8) | .01 | .03 |
Right atrial area, mean (SD), cm2/m2 | 11.4 (2.1) | 10.3 (2.0) | .01 | .01 |
Pulmonary artery area, cm2/m2 | 3.9 (3.4-4.3) | 3.7 (3.3-4.3) | .37 | .11 |
LV function | ||||
LV ejection fraction, % | 60.2 (56.8-63.6) | 59.2 (55.7-61.8) | .04 | .01 |
LV cardiac index, mL/min/m2 | 2.3 (3.0-3.7) | 3.2 (2.9-3.7) | .31 | .16 |
RV function | ||||
Right ejection fraction, % | 55.0 (51.6-58.5) | 56.1 (52.9-60.7) | .05 | .06 |
RV cardiac index, mean (SD), mL/min/m2 | 2.8 (0.5) | 2.8 (0.5) | .98 | .95 |
Abbreviations: EDV, end-diastolic volume; ESV, end-systolic volume; IQR, interquartile range; LV, left ventricle; RV, right ventricle; SGA, small for gestational age.
P value as compared with controls adjusted for age, sex, asthma, educational level, smoking habit, gestational age at delivery, breastfeeding, and gestational hypertension.
Cardiac dimensions, volumes, mass, and output were indexed for body surface area.
Ventricular sphericity indices were calculated as base-to-apex length divided by the basal diameter.
Relative wall thickness was calculated as (posterior LV wall thickness × 2)/end-diastolic LV cavity diameter.