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. 2021 Jul 21;6(11):1–9. doi: 10.1001/jamacardio.2021.2537

Table 2. Cardiac Magnetic Resonance Results for the Study Populations.

Measure Median (IQR) P value Adjusted P valuea
Control (n = 77) Born SGA (n = 81)
Left morphometry b
LVEDV, mean (SD), mL/m2 86.6 (12.8) 83.4 (12.2) .10 .27
LVESV, mean (SD), mL/m2 34.5 (7.2) 34.3 (6.5) .91 .49
LV base-to-apex length, mm/m2 5.0 (4.7-5.3) 5.0 (4.7-5.5) .11 .53
LV basal diameter, mm/m2 25.6 (23.8-27.0) 25.9 (24.1-27.1) .29 .72
LV sphericity index, mean (SD)c 0.4 (0.1) 0.4 (0.1) .98 .62
Relative wall thicknessd 2.3 (2.0-2.5) 2.2 (1.9-2.6) .63 .62
LV mass, mean (SD), g/m2 47.8 (11.9) 45.4 (8.8) .25 .64
Left atrial area, cm2/m2 12.6 (11.7-13.7) 12.3 (10.9-14.3) .50 .29
Aortic area, mean (SD), cm2/m2 3.6 (0.6) 3.7 (0.7) .26 .66
Right morphometry b
RVEDV, mean (SD), mL/m2 78.8 (15.1) 74.1 (13.8) .04 .13
RVESV, mL/m2 34.4 (28.3-42.9) 32.1 (27-36.8) .01 .03
Right atrial area, mean (SD), cm2/m2 11.4 (2.1) 10.3 (2.0) .01 .01
Pulmonary artery area, cm2/m2 3.9 (3.4-4.3) 3.7 (3.3-4.3) .37 .11
LV function
LV ejection fraction, % 60.2 (56.8-63.6) 59.2 (55.7-61.8) .04 .01
LV cardiac index, mL/min/m2 2.3 (3.0-3.7) 3.2 (2.9-3.7) .31 .16
RV function
Right ejection fraction, % 55.0 (51.6-58.5) 56.1 (52.9-60.7) .05 .06
RV cardiac index, mean (SD), mL/min/m2 2.8 (0.5) 2.8 (0.5) .98 .95

Abbreviations: EDV, end-diastolic volume; ESV, end-systolic volume; IQR, interquartile range; LV, left ventricle; RV, right ventricle; SGA, small for gestational age.

a

P value as compared with controls adjusted for age, sex, asthma, educational level, smoking habit, gestational age at delivery, breastfeeding, and gestational hypertension.

b

Cardiac dimensions, volumes, mass, and output were indexed for body surface area.

c

Ventricular sphericity indices were calculated as base-to-apex length divided by the basal diameter.

d

Relative wall thickness was calculated as (posterior LV wall thickness × 2)/end-diastolic LV cavity diameter.