Fig. 1.

(A) Chest computed tomography (CT) three months before the onset in Patient 1 showing emphysema and ground-glass opacities in the lower lobes, which was histologically diagnosed as desquamative interstitial pneumonia. (B) Chest CT two weeks after vaccination in Patient 1, showing diffuse and patchy ground-glass opacities and irregular reticulation with relative subpleural sparing in the lower lobes. (C) Chest CT 18 months before the onset in Patient 2, showing mild reticulation in the lower lobes. (D) Chest CT one month after vaccination in Patient 2, showing diffuse ground-glass opacities and reticular shadows in subpleural predominance. (E) Chest CT three months before the onset in Patient 3, showing no abnormalities. (F) Chest CT 10 days after the second vaccination in Patient 3, showing patchy bilateral air-space consolidation and linear opacities with subpleural and peribronchial distribution.