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Overexpression of miR-34a promotes fibrosis of HSCs. (A) The level of miR-34a in the HSCs transfected with miR-34a mimics; (B) TGF-β, α-SMA, MCP-1, and PDGFR were up-regulated by miR-34a mimics; (C) HSCs that overexpressed miR-34a became fibrotic at 14 days. Scale bar =100 µm. **, P<0.01. HSCs, hepatic stellate cells.
