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Knockdown of miR-34a inhibited CCl4-induced liver fibrosis. (A) CCl4-induced increased miR-34a expression in mice; (B) the addition of miR-34a siRNA inhibited the increase of miR-34a expression in CCl4-induced mice; (C,D) CCl4-induced increased TGF-β, α-SMA, and MCP-1 in mice. After injecting with CCl4 and siRNA, the expression of TGF-β, α-SMA, and MCP-1 was decreased. **, P<0.01.
