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. 2021 Oct;9(20):1556. doi: 10.21037/atm-21-4669

Table 5. Predictive performance of CT features.

Variables AUC (95% CI) Sensitivity (95% CI) Specificity (95% CI) P value Cut-off value
Borders 0.583 (0.511–0.653) 43.1% (30.2–56.8%) 73.6% (65.5–80.7%) 0.027
Enhancement patterns 0.609 (0.537–0.677) 89.7% (78.8–96.1%) 32.1% (24.5–40.6%) 0.0001
Air density in mass 0.652 (0.581–0.718) 39.7% (27.0–53.4%) 90.7% (84.6–90.7%) <0.0001
Ulceration 0.646 (0.575–0.712) 44.8% (31.7–58.5%) 84.3% (77.2–89.9%) 0.0001
EVFDM 0.655 (0.585–0.721) 89.7% (78.8–96.1%) 41.4% (33.2–50.1%) <0.0001
Necrosis 0.802 (0.740–0.855) 69.0% (55.5–80.5%) 91.4% (85.5–95.5%) <0.0001
Cystic degeneration 0.563 (0.491–0.633) 15.5% (7.3–27.4%) 97.1% (92.8–99.2%) 0.011
Hemorrhage 0.565 (0.493–0.635) 17.2% (8.6–29.4%) 95.7% (90.9–98.4%) 0.014
HYOM 0.773 (0.709–0.830) 89.7% (78.8–96.1%) 65.0% (56.5–72.9%) <0.0001
Adjacent organ invasion 0.647 (0.576–0.713) 29.3% (18.1–42.7%) 100.0% (97.4–100.0%) <0.0001
Lymphadenopathy 0.539 (0.467–0.610) 12.1% (5.0–23.3%) 95.7% (90.9–98.4%) 0.094
Metastasis 0.534 (0.462–0.606) 6.9% (1.9–16.7%) 100.0% (97.4–100.0%) 0.039
Peritonitis 0.570 (0.498–0.640) 15.5% (7.3–27.4%) 98.6% (94.9–99.8%) 0.004
Ascites 0.610 (0.538–0.678) 24.1% (13.9–37.2%) 97.7% (93.9–99.6%) 0.0001
Rupture 0.639 (0.568–0.706) 29.3% (18.1–42.7%) 98.6% (94.9–99.8%) <0.0001
LD (mm) 0.705 (0.637–0.768) 86.2% (74.6–93.9%) 50.0% (41.4–58.6%) <0.0001 >38
SD (mm) 0.684 (0.614–0.748) 75.9% (62.8–82.1%) 57.9% (49.2–66.1%) <0.0001 >36
LD/SD 0.576 (0.504–0.645) 43.1% (30.2–56.8%) 73.6% (65.5–80.7%) 0.105 >1.33
Tp (HU) 0.639 (0.568–0.706) 65.5% (51.9–77.5%) 60.7% (52.1–68.9%) 0.001 ≤32
Necrosis degree (%) 0.795 (0.732–0.849) 69.0% (55.5–80.5%) 92.1% (86.3–96.0%) <0.0001 >0
Wall thickness of necrosis (mm) 0.838 (0.627–0.975) 76.9% (46.2–95.0%) 80.0% (44.4–97.5%) 0.0002 >4
Diameter of EVFDM (mm) 0.656 (0.586–0.722) 89.7% (78.8–96.1%) 41.4% (33.2–50.1%) 0.0001 >0

AUC, area under the curve; CI, confidential interval; EVFDM, enlarged vasculature feeding or draining the mass; HYOM, hyperenhancement of the overlying mucosa; LD, long diameter; SD, short diameter; Tp, tumor attenuation in plain phase.