Table 2. Baseline characteristics of adult females by uric acid levels.
Characteristics | UA <6.0 mg/dL | 6.0 mg/dL ≤ UA <7.0 mg/dL | 7.0 mg/dL ≤ UA <8.0 mg/dL | UA ≥8.0 mg/dL | P |
---|---|---|---|---|---|
N (% of all females) | 165,678 (88%) | 12,512 (6.6%) | 5,028 (2.7%) | 4,981 (2.6%) | |
Demographics | |||||
Age (years) | 51.3±15.89 | 53.7±17.18 | 52.29±18.3 | 49.22±19.36 | 0.359 |
Lab examination | |||||
TG (mmol/L) | 1.14 (0.81) | 1.54 (1.06) | 1.64 (1.2) | 1.51 (1.19) | <0.001 |
TC (mmol/L) | 4.83±1.07 | 5.07±1.16 | 5.02±1.22 | 4.76±1.33 | <0.001 |
HDL-C (mmol/L) | 1.29±0.33 | 1.2±0.32 | 1.16±0.32 | 1.09±0.39 | <0.001 |
LDL-C (mmol/L) | 2.83±0.85 | 3±0.9 | 2.96±0.95 | 2.79±1.00 | <0.001 |
CRP (mg/L) | 4.1 (17.4) | 4.35 (12.96) | 4.43 (15.03) | 4.99 (16.54) | 0.078 |
Glucose (mmol/L) | 5.24 (1.18) | 5.43 (1.46) | 5.42 (1.49) | 5.3 (1.4) | <0.001 |
HbA1c (%) | 6.0 (1.6) | 6.3 (1.6) | 6.3 (1.5) | 6.4 (1.7) | <0.001 |
eGFR (mL/min/1.73 m2) | 103.57±19.73 | 90.37±28.32 | 86.04±33.37 | 83.47±38.28 | <0.001 |
SBP (mmHg) | 127.68±18.86 | 129.96±19.47 | 130.39±21.4 | 129.68±23.67 | <0.001 |
DBP (mmHg) | 76.43±11.16 | 77.83±11.86 | 78.54±13.22 | 76.57±13.94 | <0.001 |
Comorbidities (%) | |||||
Hyperuricemia | 0.1 | 100 | 100 | 100 | <0.001 |
Gout | 0.1 | 0.3 | 0.6 | 1.6 | <0.001 |
Dyslipidemia | 42.3 | 57.8 | 58.9 | 51 | <0.001 |
Type 2 diabetes mellitus | 10.8 | 13.7 | 14.1 | 13.1 | <0.001 |
Hypertension | 25.5 | 33.6 | 36.6 | 36.5 | <0.001 |
Cardio-cerebrovascular disease | 23.1 | 28.9 | 30.1 | 33.2 | <0.001 |
Stroke | 7.8 | 8 | 8.4 | 9.8 | <0.001 |
Coronary arterial disease | 17.5 | 23.6 | 24 | 25.8 | <0.001 |
Heart failure | 7.5 | 11.3 | 13.4 | 17.4 | <0.001 |
Chronic kidney disease | 1.6 | 5.2 | 10 | 12.7 | <0.001 |
Calculus of kidney and ureter | 0.8 | 0.8 | 0.6 | 1.1 | 0.618 |
CRP, C-reactive protein; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides.