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. 2021 Oct;9(20):1550. doi: 10.21037/atm-21-5052

Table 6. Multivariate linear regression analysis of the association between change of serum uric acid from baseline and change of metabolism-related biochemical measurements from baseline among males and females.

Variables Male Female
β 95% CI P value β 95% CI P value
eGFRa −4.199 −4.315 to −4.082 <0.001 −4.464 −4.599 to −4.329 <0.001
TCa 0.053 0.046–0.061 <0.001 0.067 0.058–0.076 <0.001
TGb 0.065 0.059–0.071 <0.001 0.078 0.071–0.085 <0.001
LDL-Cc 0.038 0.032–0.044 <0.001 0.042 0.037–0.047 <0.001
HDL-Cd 0.001 −0.002–0.003 0.607 −0.005 −0.008 to −0.002 <0.001
Glucosee 0.040 0.023–0.058 <0.001 0.037 0.017–0.056 <0.001
HbA1ce −0.035 −0.052 to −0.018 <0.001 −0.030 −0.048 to −0.011 0.002

a, adjusted for sex, age, center, hypertension, TG, HDL-C, LDL-C, and glucose; b, adjusted for sex, age, center, hypertension, TC, HDL-C, LDL-C, and glucose; c, adjusted for sex, age, center, hypertension, TC, TG, HDL-C, and glucose; d, adjusted for sex, age, center, hypertension, TC, TG, LDL-C, and glucose; e, adjusted for sex, age, center, hypertension, TG, HDL-C, and LDL-C. CRP, C-reactive protein; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides.