Table 6. Multivariate linear regression analysis of the association between change of serum uric acid from baseline and change of metabolism-related biochemical measurements from baseline among males and females.
Variables | Male | Female | |||||
---|---|---|---|---|---|---|---|
β | 95% CI | P value | β | 95% CI | P value | ||
eGFRa | −4.199 | −4.315 to −4.082 | <0.001 | −4.464 | −4.599 to −4.329 | <0.001 | |
TCa | 0.053 | 0.046–0.061 | <0.001 | 0.067 | 0.058–0.076 | <0.001 | |
TGb | 0.065 | 0.059–0.071 | <0.001 | 0.078 | 0.071–0.085 | <0.001 | |
LDL-Cc | 0.038 | 0.032–0.044 | <0.001 | 0.042 | 0.037–0.047 | <0.001 | |
HDL-Cd | 0.001 | −0.002–0.003 | 0.607 | −0.005 | −0.008 to −0.002 | <0.001 | |
Glucosee | 0.040 | 0.023–0.058 | <0.001 | 0.037 | 0.017–0.056 | <0.001 | |
HbA1ce | −0.035 | −0.052 to −0.018 | <0.001 | −0.030 | −0.048 to −0.011 | 0.002 |
a, adjusted for sex, age, center, hypertension, TG, HDL-C, LDL-C, and glucose; b, adjusted for sex, age, center, hypertension, TC, HDL-C, LDL-C, and glucose; c, adjusted for sex, age, center, hypertension, TC, TG, HDL-C, and glucose; d, adjusted for sex, age, center, hypertension, TC, TG, LDL-C, and glucose; e, adjusted for sex, age, center, hypertension, TG, HDL-C, and LDL-C. CRP, C-reactive protein; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides.