Table 2. Subregions of the CC showing significant differences in DTI indices and volume between the OHE, noHE, and HC groups.
| Indices | Region | OHE (n=26) | noHE (n=31) | HCs (n=30) | F | P | Post hoc comparison |
|---|---|---|---|---|---|---|---|
| FA | CC-5 | 0.49223±0.06658 | 0.45925±0.09463 | 0.54490±0.06856 | 9.228 | 0.000 | OHE < HC, noHE < HC |
| Volume (cm3) | CC-1 | 0.83300±0.08516 | 0.88577±0.01617 | 0.88886±0.01689 | 11.461 | 0.000 | OHE < HC, OHE < noHE |
| CC-2 | 0.80792±0.09702 | 0.85690±0.02350 | 0.85866±0.02120 | 7.188 | 0.001 | OHE < HC, OHE < noHE | |
| CC-3 | 0.79873±0.14470 | 0.85664±0.03194 | 0.85710±0.02883 | 4.476 | 0.014 | OHE < HC, OHE < noHE | |
| CC-4 | 0.78635±0.16055 | 0.84603±0.04083 | 0.84590±0.03589 | 3.718 | 0.028 | OHE < HC, OHE < noHE | |
| CC-5 | 0.80034±0.07107 | 0.85096±0.01405 | 0.84860 ± 0.01371 | 13.629 | 0.000 | OHE < HC, OHE < noHE |
DTI, diffusion tensor imaging; OHE, overt hepatic encephalopathy; noHE, cirrhosis without HE; HCs, healthy controls; CC, corpus callosum; FA, fractional anisotropy.