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. 2021 Oct 26;86(21):14928–14941. doi: 10.1021/acs.joc.1c01629

Table 2. Scope of Different ArMgBr Reagents in the Reaction with Triflate 5aa,b,c.

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a

Reaction conditions: 5a (0.13 mmol), ArMgBr (0.195 mmol), THF (2 mL).

b

Isolated yields of product.

c

Numbers in parentheses indicate yields according to 31P NMR.

d

Reaction was carried out on a 0.6 mmol scale.

e

Reaction was carried out with o-TolMgCl.

f

Formation of a small amount of ketone 3a was observed but not isolated.

g

Additionally, 7% of 3a was isolated.