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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Resuscitation. 2021 Mar 30;163:6–13. doi: 10.1016/j.resuscitation.2021.03.020

Table 3.

Interaction Model between Sex and each Covariate by Study Outcomes, adjusted for covariates.

Survival to Hospital Admission Survival to Hospital Discharge Favorable Survival Neurological

Stratum OR (95% CI) P value for interaction OR (95% CI) P value for interaction OR (95% CI) P value for interaction

Age strata <0.001 <0.001 <0.001
Among Age <50 0.69 (0.66 – 0.72) 0.76 (0.72 – 0.80) 0.80 (0.75 – 0.84)
Among Age ≥50 0.79 (0.77– 0.81) 0.89 (0.86 – 0.92) 0.95 (0.92 – 0.99)

Race strata 0.41 0.008 0.24
Among Blacks 0.76 (0.72 – 0.79) 0.75 (0.71 – 0.80) 0.86 (0.81 – 0.92)
Among Whites 0.74 (0.72 – 0.76) 0.84 (0.81 – 0.88) 0.88 (0.84 – 0.92)
Among Hispanics 0.75 (0.68 – 0.84) 0.78 (0.67 – 0.90) 0.86 (0.73 – 1.01)
Among Others 0.80 (0.71 – 0.90) 1.00 (0.84 – 1.19) 1.10 (0.91 – 1.34)
Among Unknown 0.76 (0.74 – 0.80) 0.85 (0.80 – 0.90) 0.87 (0.82 – 0.92)

AED shock 0.12 0.47 0.93
Among those w/ AED shock 0.72 (0.68 – 0.76) 0.84 (0.79 – 0.90) 0.88 (0.82 – 0.94)
Among those w/o AED shock 0.75 (0.74 – 0.77) 0.82 (0.79 – 0.85) 0.88 (0.84 – 0.91)

Shockable rhythm <0.001 0.77 0.80
Among those w/ shockable 0.70 (0.68 – 0.73) 0.82 (0.79 – 0.86) 0.88 (0.84 – 0.92)
Among those w/o shockable 0.76 (0.75 – 0.78) 0.82 (0.79 – 0.86) 0.88 (0.84 – 0.92)

Witnessed 0.003 0.22 0.29
Among witnessed 0.73 (0.71 – 0.75) 0.81 (0.77 – 0.85) 0.86 (0.81 – 0.91)
Among those w/o Bystander CPR 0.73 (0.71 – 0.75) 0.76 (0.73 – 0.80) 0.82 (0.78 – 0.85)

Bystander CPR <0.001 <0.001 <0.001
Among those w/ Bystander CPR 0.79 (0.76 – 0.81) 0.90 (0.86 – 0.93) 0.94 (0.90 – 0.98)
Among those w/o Bystander CPR 0.73 (0.71 – 0.75) 0.76 (0.73 – 0.80) 0.82 (0.78 – 0.85)

Public location of Arrest 0.02 0.33 0.71
Among those in public location 0.71 (0.68 – 0.75) 0.84 (0.80 – 0.89) 0.87 (0.82 – 0.92)
Among those in private location 0.76 (0.74 – 0.78) 0.82 (0.79 – 0.85) 0.88 (0.85 – 0.92)

Cardiac Etiology <0.001 <0.001 <0.001
Among those w/ Cardiac Etiology 0.77 (0.76 – 0.79) 0.86 (0.83 – 0.89) 0.91 (0.88 – 0.95)
Among those w/o Cardiac Etiology 0.67 (0.64 – 0.70) 0.72 (0.68 – 0.77) 0.77 (0.71 – 0.82)