Table 4.

Recurrence timing and frequency for each recurrence pattern at each tumor regression grade

Patient groups	Recurrence number		0–12 months	13–24 months	25–36 months	37–48 months	49–60 months	Median (months)
TRG1	All	22	12 (54.5%)	8 (36.4%)	2 (9.1%)	0	0	10.5 (4–26)
	Locoregional	8	5 (62.5%)	3 (37.5%)	0	0	0	9.5 (6–20)
	Distant	14	7 (50%)	5 (35.7%)	2 (14.3%)	0	0	11.5 (4–26)
TRG2	All	22	9 (40.9%)	6 (27.3%)	2 (9.1%)	4 (18.2%)	1 (4.5%)	15 (2–50)
	Locoregional	2	0	1 (50%)	0	1 (50%)	0	–
	Distant	20	9 (45%)	5 (25%)	2 (10%)	3 (15%)	1 (5%)	15 (2–50)
TRG3	All	5	3 (60%)	0	2 (40%)	0	0	12 (6–31)
	Locoregional	0	0	0	0	0	0	–
	Distant	5	3 (60%)	0	2 (40%)	0	0	12 (6–31)

TRG, tumor regression grade