Table 1.

Summary of differentially expresses genes resulting from RNA-seq comparisons of cerebellum (Cb) and fore- and mid-brain (F/M) regions between Tpp1^−/− (T) and control animals (C) at different ages

Month	% of reads mapped	Mouse gene analyzed	Brain region	DEG T vs C	DEG down T vs C	DEG up T vs C
1*	88.7	14,681	F/M	2 (126)	2 (84)	0 (42)
			Cb	2 (255)	2 (65)	0 (190)
2	87.2	14,081	F/M	139	25	114
			Cb	339	292	47
3	88.1	14,575	F/M	89	11	78
			Cb	154	31	123
4	88.3	14,923	F/M	510	171	339
			Cb	1550	553	1071

*At 1 month few DEGs genes were detected using FDR-corrected p-values; raw p-values were considered instead in the threshold (p < 0.1) only at 1-month-old (number in parenthesis)