Table 1.

Relationships between miR-378a-3p expression and clinicopathological characteristics of HCC patients

Clinicopathological characteristics	n	Low expression	High expression	P value
Total	108	54	54
Gender				0.060
Male	75	33	42
Female	33	21	12
Age (years)				0.440
≤ 60	83	41	42
> 60	25	13	12
Grade of differentiation				0.123
Low	56	32	24
High-Middle	52	22	30
Tumor diameter (cm)				0.123
≤ 5	50	29	21
> 5	58	25	33
Liver function (Child-Pugh stage)				0.588
A	92	45	47
B or C	16	9	7
Hepatocirrhosis				0.288
Absent	31	13	18
Present	77	41	36
HBV infection				0.555
Absent	43	20	23
Present	65	34	31
Thrombosis of tumor blood vessel				0.011
Absent	65	26	39
Present	43	28	15
AFP (ng/ml)				0.083
≤ 20	53	22	31
> 20	55	32	23
BCLC stage				0.552
A	41	19	22
B, C, or D	67	35	32
Envelope				0.700
Absent	52	25	27
Present	56	29	27
Tumor satellite				0.079
Absent	63	27	36
Present	45	27	18
MVD				< 0.001
High	59	45	14
Low	49	9	40

AFP serum alpha fetoprotein, HBV hepatitis B virus, BCLC Barcelona Clinic Liver Cancer