Fig. 2.

The expression level of plasma exosomal circUSP7 is upregulated in NSCLC patients. a The expression level of circUSP7 in the NSCLC tissues and preoperative plasma exosomes of NSCLC patients (R² = 0.7023; P < 0.0001). b Exosomal circUSP7 expression in the plasma of healthy donors, patients before surgery, patients after surgery, and patients with recurrence. c The expression of plasma exosomal circUSP7 in the PDX or control group. d A negative correlation between the circUSP7 expression in plasma exosomes and the proportion of CD8⁺ T cells was observed in NSCLC patient tissues (R² = 0.1080; P = 0.0002). The data are presented as the mean ± SD; n = 3, *P < 0.05, **P < 0.01