Table 3.
Univariate and Multivariate Analyses of Factors Associated with Cumulative Recurrence
| Factors | Cumulative Recurrence | |||
|---|---|---|---|---|
| Multivariate | ||||
| Univariate p | HR | 95%CI | P value | |
| Sex (Female vs. Male) | 0.617 | NA | ||
| Age (years) (≤60 vs. > 60) | 0.987 | NA | ||
| Smoking status (Smokers vs. Nonsmokers) | 0.669 | NA | ||
| Histological type (SCC vs. Adenocarcinomas) | 0.535 | NA | ||
| Lymph node metastasis (Yes vs. No) | 0.001 | 0.394 | 0.225–0.689 | 0.043 |
| Differentiation (Well and moderate vs. Poor) | 0.012 | NS | ||
| Tumor size (diameter, cm) (> 3 vs. ≤3) | 0.103 | NA | ||
| TNM (III-IV vs. I-II) | 0.098 | NS | ||
| CircUSP7 expression (High vs. Low) | 0.006 | 2.537 | 1.300–4.949 | 0.051 |
NA Not adopted, NS Not significantly, SCC Squamous cell carcinoma, 95%CI 95% confidence interval, HR hazard ratio; Cox proportional hazards regression model