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. 2021 Nov 8;18:49. doi: 10.1186/s12987-021-00281-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Representative T2-weighted axial MRI images summarizing brain and ventricular morphology in non-hydrocephalic control (A–C) and hydrocephalic pre-shunt (A′-C′) pigs. The intact control piglet (case 25) is 41-days old. Pre-shunt images are taken from case 13 at 18-days post-kaolin. In the pre-shunt condition, note the enlargement of all cerebral ventricles and the cisterna magna (CM), prominent flow voids (black) within the foramina of Monro (FM) and third ventricle indicative of high CSF pulsatility, the large olfactory ventricle (OV), and the choroid plexus (CP) in the lateral ventricle (LV). 4—fourth ventricle, H—hippocampus, LVt—temporal horn of the lateral ventricle. Scale bar = 10 mm for all panels