Table 4.
Decimal reduction time (D) for C. acnes and S. epidermidis viability
| TH (mg/mL) | TH-NP (mg/mL) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 | 0.50 | 1.00 | 0.25 | 0.50 | 1.00 | |||||||
| C. acnes | ||||||||||||
| r2 | 0.9654 | 0.9743 | 0.9812 | 0.9964 | 0.9984 | 0.9949 | ||||||
| k (logCFU/h) | 1.00 ± 0.11 | 2.03 ± 0.19 | 3.48 ± 0.08 | 1.02 ± 0.12 | 1.96 ± 0.43 | 3.44 ± 0.03 | ||||||
| D (min) | 60.5 ± 6.5 | 29.6 ± 2.7 | 17.3 ± 0.4 | 59.0 ± 7.0 | 31.4 ± 6.9 | 17.4 ± 0.1 | ||||||
| S. epidermidis | ||||||||||||
| r2 | 0.9944 | 0.9886 | ||||||||||
| k (logCFU/h) | 1.75 ± 0.02 | 0.54 ± 0.01 | ||||||||||
| D (min) | 34.2 ± 0.4 | 111.1 ± 2.9*$ | ||||||||||
CFU: colony forming units. One-way ANOVA (t test): statistically significant differences *p > 0.001 versus TH, $p > 0.0001 against C. acnes, same dosages