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. 2021 Jan 26;23(6):562–571. doi: 10.4103/aja.aja_86_20

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Copyright: © The Author(s)(2021)

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Meiotic recombination is integrated into the development of chromosome structure. (a) Meiotic recombination. Usually, many DSBs occur in a nucleus. But, only a few of them are repaired as COs (with interference) and the majority are repaired as NCOs. (b) An electron microscopy picture to show pachytene chromosomes of the moth Hyalophora columbia.149 The copyright license of reproducing this picture was received from the publisher Elsevier. (c) Cartoon for meiotic chromosome organization. (d) The tethered loop-axis complex brings DNA from loops to axes to generate DSBs and one DSB end is released to search for and bring its homolog into proximity. DSB: double-strand breaks; CO: crossover; NCO: noncrossover.