FIG 5.

Directional GMM recovers spatial dynamics in the cecum. (A) Selected model and corresponding locations of latent clusters in the cecum. (B) Scatterplot of projected MaPS-seq samples assigned to cecal tip-associated clusters (blue) and cecal base-associated clusters (red). (C) Clusters associated with the cecal tip have lower relative abundances of Bacteroidetes and higher relative abundances of Actinobacteria than the cecal base. (D) Selected model and corresponding locations of mixtures in the cecum. (E) Scatterplot of projected MaPS-seq samples assigned to cecal crypt-associated clusters (brown) and cecal lumen-associated clusters (pink). (F) Firmicutes are enriched in the lumen clusters compared to the crypt clusters.