Table 1.

Summary of key studies on severe acute respiratory syndrome coronavirus 2 infection neuropathology

Reference	Number of cases	Macroscopic evaluation	Microscopic evaluation
Matschke et al.[27]	43	Edema, infarcts	Ischemic infarct; astrogliosis, microgliosis, perivascular and leptomeningeal T cells
Solomon et al.[29]	18	Atherosclerosis	Hypoxic/ischemic injury; rare foci of perivascular lymphocytes and leptomeningeal inflammation
Hanley [30]	10	Ischemia; 1 brain with evidence of brainstem encephalitis	Activation of glial cells, perivascular T-lymphocyte activation
Remmelink et al. 2020 [31]	17	Ischemia, hemorrhage, edema	Spongiosis, vascular congestion