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. 2021 Nov 1;13(1):e2021068. doi: 10.4084/MJHID.2021.068

Table 4.

Factors that can lead to mast cells mediators release.114

  • 1. Physical agents

  • Heat

  • Cold

  • Pressure or rubbing of skin lesions

  • 2. Emotional factors

  • Fatigue

  • Anxiety

  • 3. Drugs and medications

  • Acetylsalicylic acid

  • Non-Steroidal Anti-Inflammatory Drugs

  • Cough suppressants

  • Alcohol

  • Muscle relaxants used in general anesthesia

  • Inductors used in general anesthesia

  • Local anesthetics

  • Contrasts iodized

  • alpha-adrenergic

  • beta-adrenergic blockers

  • antagonists of cholinergic receptor

  • Interferon alpha

  • 4. Poisons

  • Hymenoptera

  • Snake

  • 5. Others

  • High molecular weight molecules used in case of hypotension o hypovolemia such as dextran.