TABLE 2.
Multivariable Analysis Including Demographics, Ethnicity, Comorbidity and Baseline Disease Severity (Model 2)
| Intensive care unit | Mortality | ||||
|---|---|---|---|---|---|
| Odds ratio (95% CI) | P value | Odds ratio (95% CI) | P value | ||
| (Intercept) | 0.11 (0.08-0.15) | <.001 | (Intercept) | 0.01 (0-0.01) | <.001 |
| Age: 50–64 y | 1.18 (0.96-1.46) | .1 | Age: 50–64 y | 2.61 (1.7-4) | <.001 |
| Age: 65–79 y | 1.18 (0.96-1.46) | .1 | Age: 65–79 y | 3.99 (2.64-6.03) | <.001 |
| Age: ≥80 y | 0.82 (0.63-1.05) | .1 | Age: ≥ 80 y | 5.39 (3.48-8.37) | <.001 |
| Sex: female | 0.83 (0.72-0.96) | .01 | Sex: female | 0.83 (0.67-1.03) | .1 |
| Hispanic, English speakinga | 1.20 (0.98-1.47) | .08 | Hispanic, English-speakinga | 1.54 (1.14-2.09) | .005 |
| Hispanic, non-English speakinga | 1.47 (1.18-1.84) | <.001 | Hispanic, non-English-speakinga | 1.34 (0.97-1.87) | .08 |
| Diabetesb | 1.22 (1.05-1.42) | .01 | COPD | 1.44 (1.08-1.93) | .01 |
| COPD | 1.27 (1-1.6) | .05 | Asthma | 0.69 (0.45-1.06) | .09 |
| Heart failure | 1.34 (1.06-1.69) | .01 | Heart failure | 1.34 (1.01-1.78) | .04 |
| Kidney disease without ESRD | 2.50 (2.12-2.94) | <.001 | Kidney disease without ESRD | 3.22 (2.55-4.06) | <.001 |
| Liver disease | 1.58 (1.2-2.09) | .001 | ESRD | 1.35 (0.9-2.01) | 0.14 |
| Severe baseline condition | 4.52 (3.83-5.33) | <.001 | Liver disease | 2.62 (1.84-3.71) | <.001 |
| Smoker | 1.40 (1.11-1.76) | .004 | |||
| Severe baseline condition | 3.32 (2.67-4.13) | <.001 | |||
Variables included in the analysis were determined through a backward stepwise variable selection process (see details in Methods). Variable selection was performed independently for the two models with intensive care unit and mortality, respectively, as outcome.
a
Reference: Non-Hispanic patients.
b
Diabetes includes comorbidity code of “diabetes” or hemoglobin A1c > 9%.
Abbreviations: COPD, chronic obstructive pulmonary disease; ESRD, end-stage renal disease.