Table 4. Predictive factors for peripancreatic fluid infection after distal pancreatectomy.
| Factor | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| B-intervention | B-intervention | P-value | β | Odds ratio | CI | P-value | |
| Non-infected (n = 35) | Infected (n = 11) | ||||||
| Preoperative characteristics | |||||||
| Sex, male/female | 24/11 | 6/5 | 0.307 | ||||
| Age, years | 68 (41–89) | 64 (20–88) | 0.820 | ||||
| BMI, kg/m2 | 22.9 (15.4–34.7) | 22.7 (15.8–27.3) | 0.924 | ||||
| DM, n | 7 (20.0%) | 1 (9.1%) | 0.341 | ||||
| PDAC, n | 18 (51.4%) | 3 (27.3%) | 0.161 | ||||
| PNI | 46.7 (32.9–58.2) | 49.2 (34.5–53.0) | 0.188 | ||||
| Intraoperative characteristics | |||||||
| Operation time, min | 356 (201–593) | 343 (260–569) | 0.658 | ||||
| Blood loss, mL | 507 (0–2042) | 393 (5–1250) | 0.255 | ||||
| Closure method, n | 0.968 | ||||||
| Stapler | 7 (20.0%) | 2 (18.2%) | |||||
| Hand-sewn suture | 28 (80.0%) | 9 (81.8%) | |||||
| Laparoscopic surgery, n | 7 (20.0%) | 2 (18.2%) | 0.584 | ||||
| without splenectomy, n | 2 (5.7%) | 2 (18.2%) | 0.168 | ||||
| Simultaneous resection of alimentary tract, n | 3 (8.6%) | 5 (45.5%) | 0.009 | ||||
| Postoperative characteristics | |||||||
| WBC, /uL | |||||||
| POD 3 | 13,640 (6,750–25,450) | 11,930 (5,870–18,130) | 0.532 | ||||
| POD 6–7 | 10,135 (4,990–14,180) | 10,560 (8,190–13,440) | 0.350 | ||||
| Drainage day | 12,280 (4,470–28,980) | 14,110 (6,590–26,120) | 0.308 | ||||
| CRP, mg/dL | |||||||
| POD3 | 14.90 (5.15–38.18) | 15.95 (9.00–28.35) | 0.314 | ||||
| POD6-7 | 5.07 (1.47–21.25) | 9.68 (2.84–15.74) | 0.070 | ||||
| Drainage day | 10.10 (0.92–-32.60) | 13.65 (2.31–28.35) | 0.185 | ||||
| Body temperature, °C | |||||||
| POD3 | 37.2 (36.0–39.3) | 37.3 (36.2–37.9) | 0.730 | ||||
| POD6-7 | 36.9 (36.5–39.0) | 37.0 (36.5–38.9) | 0.416 | ||||
| Drainage day | 37.3 (36.3–38.6) | 36.9 (36.4–38.9) | 0.456 | ||||
| Drain removal, POD | 7 (3–45) | 8 (3–35) | 0.848 | ||||
| CT evaluation of PFCs on drainage day | |||||||
| POD | 13 (5–34) | 17 (3–29) | 0.524 | ||||
| CT value, HU | 16.1 (6.9–28.0) | 26.3 (12.5–35.9) | <0.001 | 0.311 | 1.365 | 1.101–1.692 | 0.005 |
| CT volume, ml | 91.7 (6.1–512.4) | 36.2 (10.2–182.0) | 0.025 | ||||
Data are expressed as number (percentage), median (range).
BMI: body mass index, DM: diabetes mellitus, PDAC: pancreatic ductal adenocarcinoma, PNI: prognostic nutritional index, WBC: white blood count, POD: post operative day, CRP: C-reactive protein, PFC: peripancreatic fluid collection, CT: computed tomography, HU: hounsfeild units, CI: confidence interval.