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. 2021 Oct 26;11:756854. doi: 10.3389/fcimb.2021.756854

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Copyright © 2021 Kathamuthu, Kumar, Moideen, Menon and Babu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmap analysis of γδ T cells. The cytokine and cytotoxic and immune marker frequencies were normalized across all LTB groups, and the expression data are shown. Each column indicates a single person. We show the heatmap expression of (A) GMCSF and Th1 cytokines, (B) PD-1 and Th17 cytokines, and (C) PD-1 and cytotoxic markers in LTB patients coinfected with DM (n = 20), PDM (n = 20), and NDM (n = 20) individuals upon UNS, Mtb (PPD, WCL), and positive antigen (P/I) control stimulation with continuous color shading.