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. 2021 Oct 26;9:637650. doi: 10.3389/fcell.2021.637650

TABLE 2.

Significant correlations of pretreatment CRP, GPS, and CAR with the clinicopathological features of stage I–III CRC patients.

Parameter Pretreatment CRP
Pretreatment GPS
Pretreatment CAR
r p-value r p-value r p-value
Sex 0.175 0.002 0.069 0.230 0.169 0.003
Age −0.027 0.642 0.118 0.039 −0.002 0.974
Location of primary tumor 0.199 <0.001 0.093 0.104 0.204 <0.001
Pathological differentiation −0.095 0.096 −0.056 0.331 −0.092 0.107
Pretreatment CEA (ng/ml) −0.015 0.798 0.119 0.037 −0.013 0.817
Pretreatment CA19-9 (ng/ml) 0.047 0.408 0.013 0.822 0.049 0.397
Lymphatic invasion −0.007 0.903 0.058 0.309 −0.013 0.814
Stage −0.046 0.422 0.015 0.793 −0.052 0.363

If two variables are continuous, Pearson’s correlation analysis was used. If there are two categorical variables, or one categorical and one continuous, Spearman’s correlation analysis was used. Values in bold indicate statistical significance (p < 0.05). CRP, C-reactive protein; GPS, Glasgow Prognostic Score; CAR, CRP-to-albumin ratio; CRC, colorectal cancer; CEA, carcinoembryonic antigen; CA19, carbohydrate antigen 19-9.