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. 2021 Oct 26;9:637650. doi: 10.3389/fcell.2021.637650

TABLE 3.

Significant correlations of pretreatment CRP, GPS, and CAR with the clinicopathological features of CRLM patients.

Parameter Pretreatment CRP
Pretreatment GPS
Pretreatment CAR
r p-value r p-value r p-value
Sex 0.039 0.748 −0.094 0.431 0.035 0.774
Age −0.068 0.568 0.106 0.373 0.093 0.071
Location of primary tumor 0.261 0.027 0.222 0.061 0.221 0.064
Pathological differentiation −0.100 0.401 −0.142 0.233 −0.074 0.539
Pretreatment CEA (ng/ml) 0.409 <0.001 0.346 0.003 0.390 <0.001
Pretreatment CA19-9 (ng/ml) 0.367 0.002 0.380 0.001 0.349 0.003
Lymphatic invasion −0.054 0.653 0.082 0.496 −0.019 0.876

If two variables are continuous, Pearson’s correlation analysis was used. If there are two categorical variables, or one categorical and one continuous, Spearman’s correlation analysis was used. Values in bold indicate statistical significance (p < 0.05). CRP, C-reactive protein; GPS, Glasgow Prognostic Score; CAR, CRP-to-albumin ratio; CRLM, colorectal liver metastases; CEA, carcinoembryonic antigen; CA19, carbohydrate antigen 19-9.