Table 2.
Comparison of baseline laboratory investigations of the outpatient and inpatient groups at initial presentation.
| Investigations | Outpatient group (DF)7 (n = 87) | Inpatient group (severe DF)7 (n = 6) | P value |
|---|---|---|---|
| Hemoglobin (g/dl), mean ± SD | 11.0 ± 1.1 | 11.3 ± 1.1 | 0.649 |
| Total leucocyte count (x103/μl), mean ± SD | 5235.6 ± 1218.9 | 3350 ± 665.6 | 0.020 |
| Range of total leucocyte count (x103/μl) | 2700–9500 | 2200–4700 | — |
| Total leucocyte count <4,000 (x103/μl), n (%) | 20 (23) | 6 (100) | — |
| Total platelet count (x103/μl), mean ± SD | 195.8 ± 43.4 | 65.2 ± 35.0 | 0.000 |
| Range of platelets (x103/μl) | 72,000–316,000 | 16,000–150,000 | — |
| Platelet count <150,000 (x103/μl), n (%) | 24 (28) | 6 (100) | |
| Platelet count <50,000 (x103/μl), n (%) | 0 | 6 (100) | — |
| Hematocrit (mean ± SD) | 36.4 ± 1.8 | 43.3 ± 3.9 | 0.000 |
| Range of hematocrit | 33–42 | 39–48 | |
|
| |||
| ALT raised, n/N1 (%) | |||
| Mildly raised (40–75 IU/L) | 3 (4.1) | 0 | 0.000 |
| Moderately raised (76 to 999 IU/L) | 0 | 3 (50.0) | |
| Markedly raised (≥1000 IU/L) | 0 | 0 | |
|
| |||
| AST raised–n/N2 (%) | |||
| Mildly raised (40–75 IU/L) | 3 (4.1) | 3 (50) | 0.000 |
| Moderately raised (76 to 999 IU/L) | 0 | 0 | |
| Markedly raised (≥1000 IU/L) | 0 | 0 | |
|
| |||
| CXR abnormality, n/N3 (%) | 0 | 14 (16.7) | 0.000 |
| USG abdomen abnormality, n/N5 (%) | 0 | 26 (33.3) | 0.000 |
1ALT was done in 78 patients in total (72 in outpatient and 6 in inpatient). 2AST was done in 73 patients in total (67 in outpatient and 6 in inpatient), 3CXR was done in 10 children in total (5 in outpatient and 5 in inpatient). 4Pleural effusion. 5USG abdomen was done in 13 children in total (8 in outpatient and 5 in inpatient). 6Ascites. 7All these children had DF according to WHO criteria with NS1Ag confirmation. 7All these children had SD, according to WHO criteria at presentation with NS1Ag confirmation.