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. 2021 Oct 1;296:567–576. doi: 10.1016/j.jad.2021.09.098

Table 1.

Standardized mean change in symptoms when mental health was measured earlier vs. later in the pandemic.

Symptom March-April effect estimate May – July effect estimate Symptoms by month time trend analysis
Anxiety disorder symptoms (n = 52) n = 29, SMC = .140 [95% CI: -.024 to .303, I2 = 97.4%] n = 23, SMC = .051 [95% CI: -.037 to .139, I2 = 87.9%] Coefficient = -.067 [95% CI: -.124 to -.009]
Depression and mood disorder symptoms (n = 58) n = 32, SMC = .226 [95% CI: .109 to .343, I2 = 95.9%] n = 26, SMC = .201 [95% CI: .099 to .302, I2 = 93.8%] Coefficient = -.057 [95% CI: -.119 to .005]
General (non-specific) mental health (n = 35) n = 20, SMC = -.013 [95% CI: -.176 to .150, I2 = 98.5%] n = 15, SMC = -.098 [95% CI: -.292 to .095, I2 = 99.3%] Coefficient = -.071 [95% CI: -.119 to .-.022]
Psychotic symptoms (n = 5) n = 5, SMC = -.211 [95%CI: -.376 to -.046, I2 = 73.1%] - -
Well-being (n = 7) n = 6, SMC = .053 [95% CI: -.182 to .288, I2 = 92.8%] - -
Other disorder specific symptoms (n = 8) n = 6, SMC = -.105 [95 CI: -.282 to .073, I2 = 84.9%] n = 2, SMC = .130 [95% CI: -.180 to .440, I2 = 88.6%] Coefficient = .105 [95% CI: -.019 to .229]

n = equals number of comparisons. Cells with - are indicative of insufficient effect sizes for individual analyses. Depression and mood disorder symptoms included depressive symptoms and emotional problems. General (non-specific) mental health measures included mental health related-quality of life, distress, internalizing symptoms. Psychotic symptoms included measures of psychoticism and paranoia. Well-being included measures of overall psychological well-being. Other disorder specific symptoms included eating disorder symptomology, post-traumatic stress disorder symptoms, suicidal ideation. For all measures included by symptom type see Table S1.