Table 5.

GAMM estimates for bilateral amygdala across both sexes in manual tracing, volBrain, FSL, CS-FS, and LG-FS segmentation separately.

	Hemisphere	Best model fit	R${}^2$(adjusted)	Sex				Age spline
				Estimate	SE	t	p-value	edf	Red.df	F	p-value
Manual	Left amygdala	s(age) $+$ sex	0.14	0.13	0.02	6.07	0.000	1.12	1.12	8.32	0.003
	Right amygdala	s(age) $+$ sex	0.12	0.12	0.02	5.86	0.000	1.38	1.38	8.47	0.001
volBrain	Left amygdala	s(age) $+$ sex	0.19	0.10	0.01	7.15	0.000	2.17	2.17	8.07	0.000
	Right amygdala	s(age) $+$ sex	0.17	0.11	0.02	6.84	0.000	1.83	1.83	7.34	0.001
CS-FS	Left amygdala	s(age) $+$ sex	0.15	0.16	0.03	6.08	0.000	1.48	1.48	0.69	0.317
	Right amygdala	s(age) $+$ sex	0.17	0.21	0.03	7.15	0.000	2.05	2.05	2.77	0.066
LG-FS	Left amygdala	s(age) $+$ sex	0.16	0.17	0.03	6.13	0.000	2.04	2.04	3.52	0.034
	Right amygdala	s(age) $+$ sex	0.20	0.24	0.03	7.81	0.000	1.89	1.89	3.42	0.022
FSL	Left amygdala	s(age)	0.11					3.15	3.15	19.48	0.000
	Right amygdala	s(age)	0.06					2.74	2.74	11.13	0.000

Note: Smooth function (edf) as well as degrees of freedom (Ref.df) and F-statistic and associated p-value (bold highlights p$<$ .05) for age.