Table 3.
Diagnostic performance of CAP for grading steatosis and diagnosing NASH (n = 112).
| AUROC (95% CI∗) | Cut-off (dB/m) | Se (95% CI) | Sp (95% CI) | PPV (95% CI) | NPV (95% CI) | |
|---|---|---|---|---|---|---|
| S0 vs. S1-3 (>5%) | 0.83 (0.72–0.93) | 316 | 0.79 (0.69–0.87) | 0.84 (0.64–0.95) | 0.95 (0.87–0.98) | 0.54 (0.37–0.70) |
| S0-1 vs. S2-3 (>33%) | 0.79 (0.70–0.88) | 316 | 0.87 (0.76–0.94) | 0.61 (0.46–0.74) | 0.73 (0.61–0.82) | 0.79 (0.64–0.91) |
| S0-2 vs. S3 (>66%) | 0.73 (0.63–0.83) | 343 | 0.77 (0.59–0.90) | 0.64 (0.53–0.75) | 0.45 (0.32–0.60) | 0.88 (0.77–0.95) |
| NASH | 0.69 (0.59–0.79) | 318 | 0.86 (0.71–0.95) | 0.47 (0.35–0.59) | 0.44 (0.33–0.57) | 0.88 (0.73–0.96) |
Values are provided with their 95% CI.
AUROC, area under the receiver operating characteristic curve; CAP, controlled attenuation parameter; NASH, non-alcoholic steatohepatitis; NPV, negative predictive value; PPV positive predictive value; Se, sensitivity; Sp, specificity.