Table 5.
Diagnostic performance of serum scores for grading steatosis (n = 145).
| AUROC (95% CI) | Cut-off | Se (95% CI) | Sp (95% CI) | PPV (95% CI) | NPV (95% CI) | |
|---|---|---|---|---|---|---|
| SteatoTest | ||||||
| S0 vs. S1-3 (>5%) | 0.74 (0.66–0.83) | 0.54 | 0.69 (0.60–0.78) | 0.65 (0.47–0.80) | 0.85 (0.76–0.92) | 0.42 (0.29–0.56) |
| S0-1 vs. S2-3 (>33%) | 0.77 (0.69–0.85) | 0.66 | 0.58 (0.45–0.69) | 0.83 (0.73–0.91) | 0.78 (0.64–0.88) | 0.66 (0.55–0.76) |
| S0-2 vs. S3 (>66%) | 0.79 (0.71–0.87) | 0.65 | 0.71 (0.54–0.85) | 0.73 (0.63–0.81) | 0.45 (0.32–0.59) | 0.89 (0.81–0.95) |
| HSI | ||||||
| S0 vs. S1-3 (>5%) | 0.73 (0.64–0.83) | 55 | 0.78 (0.70–0.86) | 0.59 (0.42–0.74) | 0.84 (0.76–0.91) | 0.49 (0.34–0.64) |
| S0-1 vs. S2-3 (>33%) | 0.68 (0.59–0.76) | 55 | 0.86 (0.77–0.93) | 0.49 (0.37–0.60) | 0.62 (0.52–0.72) | 0.79 (0.64–0.89) |
| S0-2 vs. S3 (>66%) | 0.72 (0.64–0.80) | 56 | 0.94 (0.81–0.99) | 0.45 (0.36–0.55) | 0.34 (0.25–0.45) | 0.96 (0.87–1.00) |
| FLI | ||||||
| S0 vs. S1-3 (>5%) | 0.72 (0.62–0.81) | 28.5 | 0.77 (0.68–0.84) | 0.62 (0.45–0.77) | 0.85 (0.76–0.91) | 0.49 (0.34–0.64) |
| S0-1 vs. S2-3 (>33%) | 0.65 (0.56–0.74) | 29.1 | 0.77 (0.65–0.86) | 0.50 (0.38–0.62) | 0.60 (0.50–0.70) | 0.69 (0.54–0.80) |
| S0-2 vs. S3 (>66%) | 0.68 (0.59–0.77) | 31.2 | 0.80 (0.63–0.92) | 0.54 (0.45–0.64) | 0.35 (0.25–0.47) | 0.90 (0.80–0.96) |
Values are provided with their 95% CIs.
AUROC, area under the receiver operating characteristic curve; FLI fatty liver index; HSI, hepatic steatosis index; NPV, negative predictive value; PPV positive predictive value; Se, sensitivity; Sp, specificity.