TABLE 1.
Metabolite | FC | P value | VIP | Change |
Terephthalic acid | 14.74489 | 0.025861 | 5.428705 | Up |
N-Carbamylglutamate | 7.932363 | 0.000799 | 3.026664 | Up |
5-Dihydrocortisone | 7.666312 | 0.000435 | 2.990917 | Up |
1,5-Anhydroglucitol | 7.706464 | 0.00065 | 2.970821 | Up |
7-Alpha-Hydroxycholesterol | 0.175496 | 0.00035 | 2.616602 | Down |
Sitosterol | 0.191518 | 0.000427 | 2.486919 | Down |
5-alpha-Dihydroprogesterone | 4.749013 | 0.008993 | 2.462498 | Up |
Pyridoxal phosphate | 0.187676 | 0.001927 | 2.429155 | Down |
Fluorene | 3.503161 | 0.04461 | 2.280455 | Up |
Fructose | 4.777105 | 0.002983 | 2.245097 | Up |
3,4-Dihydroxypyridine | 4.605297 | 0.001964 | 2.221375 | Up |
Nornicotine | 4.562764 | 0.00136 | 2.209108 | Up |
Indolelactate | 4.14295 | 0.001203 | 2.118684 | Up |
Anandamide | 3.819407 | 0.009658 | 2.115701 | Up |
Sucrose | 0.247109 | 0.000325 | 2.09921 | Down |
Gentiobiose | 0.261826 | 0.001422 | 2.035457 | Down |
Glucose | 0.264883 | 0.002524 | 2.033389 | Down |
Thymidine | 0.330762 | 0.032472 | 1.972127 | Down |
Prostaglandin | 3.867495 | 0.003127 | 1.959376 | Up |
Lactamide | 0.280514 | 0.003374 | 1.951068 | Down |
Lactitol | 3.667307 | 1.31E-05 | 1.929916 | Up |
D-alanyl-D-alanine | 3.534306 | 0.001807 | 1.883908 | Up |
Isomaltose | 0.282663 | 1.90E-05 | 1.87197 | Down |
Neohesperidin | 0.336693 | 0.035455 | 1.84487 | Down |
xylose | 0.295488 | 0.000167 | 1.822663 | Down |
21-hydroxypregnenolone | 0.302513 | 0.002766 | 1.812663 | Down |
Galactinol | 3.336595 | 0.000888 | 1.760767 | Up |
Coprostan-3-one | 0.312066 | 0.002056 | 1.759421 | Down |
Dihydroxyacetone | 2.932393 | 0.014074 | 1.735097 | Up |
Glucose | 0.333662 | 0.002156 | 1.665875 | Down |
Cholestane-3,5,6-triol | 0.363735 | 0.026286 | 1.665813 | Down |
N-Methyl-DL-alanine | 2.889999 | 0.000481 | 1.556525 | Up |
Salicylaldehyde | 2.628454 | 0.012711 | 1.538297 | Up |
FC, fold change; VIP, variable importance in projection. VIP > 1.5 and P-value < 0.05 were applied to determine these significantly different metabolites.