Table 3.
Surgical outcomes of patients by serum amylase on postoperative day 1 and drain fluid amylase on postoperative day 2
| SA-1 <100 N = 178 |
SA-1 >100 N = 207 |
p-value | DFA-2 <100 N = 141 |
DFA-2 >100 N = 197 |
p-value | |
|---|---|---|---|---|---|---|
| Intra-operative blood loss | 685 (315–1162) | 800.0 (500–1400) | 0.045 | 700 (400–1300) | 730.0 (400–1375) | 0.869 |
| C-reactive protein (mg/L) on postoperative day 3 | 159 (99–246) | 244 (158–325) | <0.001 | 141 (88–228) | 231 (151–316) | <0.001 |
| Days to drain removal in days | 3 (3–4) | 4 (3–7) | <0.001 | 3 (3–5) | 4 (3–6) | 0.004 |
| Length of hospital stay | 11 (8–17) | 16 (10–31) | <0.001 | 11 (8–18) | 15 (10–30) | <0.001 |
| Major morbidity (Clavien-Dindo > grade 2) | 43 (24%) | 107 (52%) | <0.001 | 36 (26%) | 93 (47%) | <0.001 |
| Postoperative mortality | 3 (1.7%) | 9 (4.3%) | 0.134 | 4 (2.8%) | 4 (2.0%) | 0.724 |
| Postoperative pancreatic fistula† | 4 (2.2%) | 79 (38%) | <0.001 | 0 (0%) | 72 (37%) | <0.001 |
| Delayed gastric emptying grade B/C¶ | 27 (15%) | 65 (31%) | <0.001 | 19 (13%) | 63 (32%) | <0.001 |
| Postpancreatectomy hemorrhage grade B/C¥ | 5 (2.8%) | 25 (12%) | <0.001 | 4 (2.8%) | 26 (13%) | <0.001 |
| Readmittance due to surgical complications | 29 (16%) | 38 (19%) | 0.549 | 22 (16%) | 39 (20%) | 0.306 |
†Grade B/C postoperative pancreatic fistula according to the International Study Group for Pancreatic Surgery criteria
¶Grade B/C delayed gastric emptying according to the International Study Group for Pancreatic Surgery criteria
¥Grade B/C post-pancreatectomy hemorrhage according to the International Study Group for Pancreatic Surgery criteria