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. 2021 Jun 18;23(6):941–951. doi: 10.1007/s11307-021-01621-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2. — (a) Representative PET/CT images at 22 h post-injection of ⁸⁹Zr-Df-IAB22M2C on day 9: 1 mg/kg isotype treated (PF-07069699, left) and GUCY2C BsAb treated (PF-07062119, right), with respective CD8+ T staining (brown; IHC, scale bar equal 50 μm). (b) Representative PET/CT images at 22 h post-injection of ⁸⁹Zr-Df-IAB22M2C exploring differences in temporal and dose response effects.