Table 2.
Baseline characteristics of patients, stratified by the presence versus absence of IVH on any hospital CT scan
| Characteristica | IVH present (n = 1249) | IVH absent (n = 1475) |
p value |
|---|---|---|---|
| Age, mean (SD), y | 62 (14) | 62 (14) | 1.0 |
| Female | 520 (42) | 609 (41) | 0.9 |
| Race | 0.048 | ||
| White | 785 (63) | 969 (66) | |
| Black | 464 (37) | 502 (34) | |
| Modified Rankin score before ICH | 0 (0–1) | 0 (0–1) | 0.3 |
| Medical history | |||
| Diabetes | 347 (28) | 419 (28) | 1.0 |
| Hypertension | 1019 (82) | 1179 (80) | 0.06 |
| Elevated cholesterol | 374 (30) | 476 (32) | 0.5 |
| CAD | 162 (13) | 190 (13) | 0.8 |
| AF | 119 (10) | 136 (9) | 0.6 |
| TIA | 60 (5) | 65 (4) | 0.5 |
| CHF | 93 (7) | 104 (7) | 0.6 |
| Home medications | |||
| Aspirin | 320 (26) | 388 (26) | 0.7 |
| Non-aspirin antiplatelet | 75 (6) | 80 (5) | 0.5 |
| Statin | 317 (25) | 349 (24) | 0.3 |
| Warfarin | 112 (9) | 130 (9) | 0.9 |
| Clinical | |||
| LOC at ICH onset | 271 (22) | 81 (6) | < 0.001 |
| Glucose value by EMS | 130 (107–165) | 125 (106–156) | 0.2 |
| ED Glasgow Coma Score | 13 (8–15) | 15 (14–15) | < 0.001 |
| ED SBP | 190 (163–218) | 180 (155–212) | < 0.001 |
| ED DBP | 104 (87–122) | 99 (83–118) | < 0.001 |
| Laboratory testing in emergency department | |||
| Serum glucose | 140 (116–177) | 122 (104–161) | < 0.001 |
| Hemoglobin | 13.8 (12.5–15.0) | 13.8 (12.6–15.0) | 0.9 |
| Platelet count | 221 (177–270) | 220 (177–263) | 0.4 |
| PTT | 28 (25–31) | 29 (26–32) | < 0.001 |
| First INR | 1.0 (1.0–1.1) | 1.0 (1.0–1.1) | 0.6 |
| CT characteristics | |||
| Initial CT ICH volume | 15 (6–39) | 8 (3–20) | < 0.001 |
| Peak ICH volume | 18 (8–43) | 9 (3–23) | < 0.001 |
| ICH expansion (> 33%) | 155 (12) | 156 (11) | 0.9 |
| Lobar hemorrhage location | 303 (24) | 515 (35) | < 0.001 |
| 3-month modified Rankin score | 3 (2–4) | 2 (1–3) | < 0.001 |
AF atrial fibrillation, CAD coronary artery disease, CHF congestive heart failure, CT computed tomography, DBP diastolic blood pressure, ED emergency department, EMS emergency medical services, ICH intracerebral hemorrhage, INR international normalized ratio, IVH intraventricular hemorrhage, LOC loss of consciousness, PTT partial thromboplastin time, SBP systolic blood pressure, SD Standard deviation, TIA transient ischemic attack, y year
aData are presented as number (%) unless otherwise specified