Table 3.

Hospital interventions, withdrawal of care and outcomes between patients with and without LOC

Hospital interventions	LOC present (n = 352)	LOC absent (n = 2372)	p value
Craniotomy for clot evacuation	44 (13)	170 (7)	0.19
ICP monitoring	154 (44)	343 (15)	< 0.001
Intraventricular drain placed	143 (41)	351 (15)	< 0.001
Shunt placement	34 (10)	97 (4)	< 0.001
Intraventricular tPA	19 (5)	31 (8)	0.01
Clinical outcome
In-hospital mortality	132 (38)	163 (7)	< 0.001
Comfort measures only (CMO)	97 (28)	187 (8)	< 0.001
3-month mRS score	4 (3–5)	3 (1–4)	< 0.001
3-month unfavorable mRS (4–6)	95 (27)	537 (23)	< 0.001
3-month Barthel score	50 (10–90)	90 (55–100)	< 0.001
EQ5D mobility	2 (2–3)	2 (1–2)	< 0.001
EQ5D self-care	2 (2–3)	2 (1–2)	< 0.001
EQ5D usual activities	2 (2–3)	2 (1–3)	< 0.001
EQ5D pain	2 (1–2)	2 (1–2)	0.09
EQ5D anxiety/depression	2 (1–2)	1 (1–2)	0.09
EQ5D health state score	60 (44–70)	70 (50–80)	< 0.001

ICP intracranial pressure, LOC loss of consciousness, mRS modified Rankin score, tPA tissue plasminogen activator