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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Ophthalmol Retina. 2021 Jul 26;5(11):1061–1073. doi: 10.1016/j.oret.2021.07.006

Table 2.

Genes used to derive each pathway-based genetic risk score.

Pathway-based genetic risk score Genes
Complement pathway C3 (3 SNPs), C9 (1 SNP), CFH (8 SNPs), CFB/C2 (4 SNPs), CFI (2 SNPs), TMEM97/VTN (1 SNP)
Lipid metabolism ABCA1 (1 SNP), APOE (2 SNPs), CETP (2 SNPs), LIPC (2 SNPs)
Extracellular matrix remodeling ADAMTS9 (1 SNP), COL4A3 (1 SNP), COL8A1 (2 SNPs), SYN3/TIMP3 (1 SNP), VEGF-A (1 SNP)
ARMS2 ARMS2 (1 SNP)