. Author manuscript; available in PMC: 2022 Nov 1.

Published in final edited form as: Ophthalmol Retina. 2021 Jul 26;5(11):1061–1073. doi: 10.1016/j.oret.2021.07.006

Table 6.

Results: p-values for pairwise comparisons of the phenotypic clusters, according to the four pathway-based genetic risk scores, by t test.

	Cross-sectional dataset				Longitudinal dataset
	A vs B		C vs D		G vs H
Pathway-based genetic risk score	Raw	Adjusted^*	Raw	Adjusted^*	Raw	Adjusted^*
Complement	0.75	1.00	0.14	1.00	0.74	1.00
Lipid metabolism	0.54	1.00	0.81	1.00	0.43	1.00
Extracellular matrix	0.86	1.00	0.16	1.00	0.086	1.00
ARMS2	0.008	0.096	0.55	1.00	0.59	1.00

Adjusted for multiple testing: adjusted for the 4 genetic risk scores by MULTTEST bootstrap and adjusted for the 3 cluster groupings by multiplying by 3.