TABLE 2.
Clinical outcomes and resource utilization in the unadjusted and propensity-matched cohorts in the transcatheter aortic valve replacement (TAVR) procedure performed without and with cerebral protection device
| Unadjusted |
Matched (1:3 Propensity match) |
|||||
|---|---|---|---|---|---|---|
| Variable n (%)a | TAVR without CPD (103,935) | TAVR with CPD (4380) | p value | TAVR without CPD (13,140) | TAVR with CPD (4380) | p value |
| In-hospital mortality | 1510(1.5) | 20(0.5) | <0.01 | 135(1.0) | 20(0.5) | <0.01 |
| Discharge disposition | ||||||
| Routine | 68,755(66.2) | 3145(71.8) | <0.01 | 8710(66.3) | 3145(71.8) | <0.01 |
| Short term care hospital | 400(0.4) | <11(<0.2) | 35(0.3) | <11(<0.3) | ||
| Home health care | 20,215(19.4) | 770(17.6) | 2580(19.6) | 770(17.6) | ||
| Complications and resource utilization | ||||||
| Cardiogenic shock | 2050(2.0) | 60(1.4) | 0.01 | 170(1.3) | 60(1.4) | 0.7 |
| Respiratory complications | 6525(6.3) | 170(3.9) | <0.01 | 745(5.7) | 170(3.9) | <0.01 |
| Acute kidney injury | 11,070(10.7) | 355(8.1) | <0.01 | 1190(9.1) | 355(8.1) | 0.05 |
| Neurological complications | 2600(2.5) | 75(1.7) | <0.01 | 340(2.6) | 75(1.7) | <0.01 |
| Hemorrhagic stroke | 115(0.1) | - | 0.03 | 20(0.2) | - | 0.01 |
| Ischemic stroke | 2070(2.0) | 60(1.4) | <0.01 | 270(2.1) | 60(1.4) | <0.01 |
| Transient ischemic attack | 305(0.3) | <11(<0.2) | 0.43 | 40(0.3) | <11(<0.3) | 0.41 |
| Vascular complications | 4380(4.2) | 175(4.0) | 0.48 | 540(4.1) | 175(4.0) | 0.74 |
| Major bleeding | 1070(1.0) | 25(0.6) | 0.003 | 95(0.7) | 25(0.6) | 0.29 |
| Cardiac arrest with CPR | 1290(1.2) | 20(0.5) | <0.01 | 125(1.0) | 20(0.5) | <0.01 |
| Prolong mechanical vent | 965(0.9) | 15(0.3) | <0.01 | 525(4.0) | 155(3.5) | 0.04 |
| Short term intubation | 3905(3.8) | 140(3.2) | 0.06 | 525(4.0) | 155(3.5) | 0.18 |
| Permanent pacemakers | 10,405(10.0) | 425(9.7) | 0.51 | 1315(10.0) | 425(9.7) | 0.56 |
| Length of stay, median (IQR), days | 2(1–4) | 2(1–4) | <0.01 | 2(1–4) | 2(1–4) | <0.01 |
| Cost of hospitalization, median (IQR) $ | 44,880(35,113–57,230) | 44,861(36,953–57,254) | <0.01 | 44,881(35,113–57,231) | 44,861(36,953–57,255) | <0.01 |
Abbreviations: CPD, cerebral protection device; TAVR; transcatheter aortic valve replacement.
Note: Major bleeding requiring blood transfusion.
a
<11 numbers not reported per HCUP recommendations.