Fig. 3. Trend test and the summary of risk factors.

A The Cochran-Armitage trend test was used to confirm the constant trend toward higher prevalence of SCD with an increasing number of risk factors. B A summary chart of risk factors was established. A total of eight factors were found associated with SCD including four stable factors proved by two multivariate models and four suggestive factors proved by one of the two multivariate models. Five of the above eight factors were verified as risk factors for SCD-plus. Abbreviations: SCD: subjective cognitive decline; HAMD: Hamilton depression scale; MDS: minimal depression symptoms.