Table 1.
Clinical data.
|
BMI (18.5–25)
(n = 23) |
BMI (25–30)
(n = 33) |
BMI ≥ 30
(n = 20) |
F
/χ2
value |
P -value | |
|---|---|---|---|---|---|
| Sex (female, %) | 8, 34.8 | 4, 12.1 | 5, 25.0 | 4.20 | 0.12 |
| Age (years) | 64.7 ± 15.3 | 68.1 ± 9.8 | 68.1 ± 9.8 | 0.68 | 0.51 |
| Hb (g/dl) | 14.19 ± 1.57 | 12.55 ± 2.22 | 18.13 ± 21.99 | 1.49 | 0.23 |
| Na+ (mmol/l) | 139.04 ± 3.47 | 139.45 ± 3.23 | 140.60 ± 3.63 | 1.19 | 0.31 |
| K+ (mmol/l) | 4.21 ± 0.65 | 4.34 ± 0.44 | 4.24 ± 0.54 | 0.43 | 0.65 |
| Creatinine (mg/dl) | 1.11 ± 1.182 | 1.23 ± 0.59 | 1.57 ± 1.88 | 0.79 | 0.46 |
| CRP (mg/l) | 6.84 ± 18.13 | 16.40 ± 34.08 | 8.46 ± 13.64 | 1.12 | 0.33 |
| TSH (uU/L) | 1.90 ± 1.42 | 1.42 ± 0.87 | 1.60 ± 0.87 | 1.12 | 0.33 |
| LVEF (%) | 50.5 ± 2.3, n = 22 | 50.0 ± 1.9 | 51.7 ± 1.8 | 0.16 | 0.85 |
| LVEDD (mm) | 49.0 ± 2.1, n = 21 | 48.3 ± 1.2, n = 32 | 49.6 ± 1.2, n = 18 | 0.17 | 0.84 |
| E/É | 10.4 ± 1.1, n = 9 | 11.4 ± 1.0, n = 12 | 14.1 ± 1.8, n = 9 | 1.98 | 0.16 |
| Co-morbidities and medication (N, %) | |||||
| Atrial fibrillation | 5, 21.7 | 5, 15.2 | 3, 15.0 | 0.48 | 0.79 |
| CAD | 16, 69.6 | 29, 87.9 | 16, 80.0 | 2.84 | 0.24 |
| Hypertension | 16, 69.6 | 26, 78.8 | 16, 80.0 | 0.82 | 0.66 |
| Diabetes | 7, 30.4 | 9, 39.1 | 2, 10.0 | 3.26 | 0.20 |
| Dyslipidemia | 8, 34.8 | 16, 48.5 | 6, 30.0 | 2.09 | 0.35 |
| Medication (N, %) | |||||
| ACEI/ARB | 18, 78.3 | 19, 57.6 | 14, 70.0 | 2.73 | 0.26 |
| Valsartan + sacubitril | 0 | 0 | 2, 10.0 | 5.49 | 0.06 |
| Spironolacton/eplerenone | 2, 8.7 | 4, 12.1 | 5, 25.0 | 2.39 | 0.30 |
| β-Blockers | 14, 60.9 | 19, 57.6 | 15, 75.0 | 1.70 | 0.43 |
| Statins | 17, 73.9 | 20, 60.6 | 16, 80.0 | 2.52 | 0.28 |
| Diuretic | 11, 47.8 | 11, 33.3 | 8, 40.0 | 1.20 | 0.55 |
| Type of surgery (N, %) | |||||
| CABGa | 18, 78.3 | 21, 63.6 | 14, 70.0 | 3.42 | 0.49 |
| Valve surgeryb | 3, 13.0 | 6, 18.2 | 5, 25.0 | ||
| CABG+ valve surgeryc | 2, 8.7 | 6, 18.2 | 1, 5.0 | ||
CABG, coronary artery bypass graft; BMI, body mass index; Hb, hemoglobin; CRP, C-reactive protein; TSH, thyroid stimulating hormone; LVEF, left ventricular ejection fraction; LVEDD, left ventricular end diastolic diameter; CAD, coronary artery disease; ACEI/ARB, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker; valve surgery refers to the heart valve replacement or heart valvuloplasty/cardiac valve repair.
a
Patients only performed CABG.
b
Patients only performed valve surgery.
c
Patients performed valve surgery and CABG; values indicate mean ± SD.