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. 2021 Nov 15;207(10):2445–2455. doi: 10.4049/jimmunol.2100566

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Copyright © 2021 by The American Association of Immunologists, Inc.

This article is distributed under The American Association of Immunologists, Inc., Reuse Terms and Conditions for Author Choice articles.

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FIGURE 2. — Term maternal versus cord blood TCR-β and IgH comparison for SHM rates, CDR3 length, and gene usage. (A) Zoom-in of V region for TCR-β and IgH. (B) V gene SHM rate in maternal versus cord blood. (C) Mean CDR3 length in maternal versus cord blood. *Adjusted p value < 0.05 by Wilcoxon rank-sum test and adjusted for multiple comparisons using the Benjamini–Hochberg procedure. (D) Applying hierarchical clustering to the V and J genes with significantly different usage results in perfect separation of maternal blood and cord blood samples into two clusters.