Table 2.

Effect of NAC supplementation on histological observation of rat salivary glands.

	C	C + NAC	HFD	HFD + NAC
Parotid glands	10 (+)	10 (+)	6 (++++), 4 (+++++)*	5 (++++), 5 (+++++)*
Submandibular glands	10 (+)	10 (+)	7 (++), 3 (+++)*	8 (++), 2 (+++)*

C control rats C + NAC control rats + N-acetylcysteine, HFD rats fed the high-fat diet, HFD + NAC rats fed the high-fat diet + N-acetylcysteine, + single vacuoles in the cytoplasm of salivary acinar cells, ++ 5–10% of each section occupied by pathological alternations, +++ 11–20% of each section occupied by pathological alternations, ++++ 21–30% of each section occupied by pathological alternations, +++++ >30% of each section occupied by pathological alternations.