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. Author manuscript; available in PMC: 2022 Nov 15.
Published in final edited form as: J Immunol. 2021 Oct 8;207(10):2589–2597. doi: 10.4049/jimmunol.2100766

Figure 5. Neutrophils (PMNs) from atopic mice inhibit development of post-viral airway disease.

Figure 5.

Depletion of PMNs with anti-Ly6G mAb 24h before (A) or 24h after (B&C) SeV infection restores post viral airway disease in atopic mice. In untreated mice, depletion of PMN with anti-Ly6G mAb 24h PI SeV had no effect on post viral airway disease (data not shown). (D) Gfp-SeV infection showed increased viral infection at d1 PI in mice depleted of Ly6G+ PMN 24 h before SeV inoculation (data are expressed as Gfp/Gapdh or SeV/Gapdh mRNA relative levels from whole lung). n≥3 mice per group.