Table 2.
CPPD Combined Expert Committee rating of influence on the likelihood of CPPD (−3 to +3) for candidate imaging items+
| Affected joint+ | Knee*+ | Wrist*+ | 2nd and/or 3rd MCP* | Hip* | Symphysis pubis* | C1/C2* | Shoulder* | |
|---|---|---|---|---|---|---|---|---|
| Plain radiograph: calcification in regions of fibro- or hyaline cartilage | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| Plain radiograph: calcification of the synovial membrane/capsule/tendon | 1** | 1** | 2 | 2 | -- | -- | 3 | -- |
| Conventional CT: calcification in regions of fibro- or hyaline cartilage | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| Conventional CT: calcification of the synovial membrane/capsule/tendon | 2 | 2 | 2 | 2 | 2 | -- | 3 | -- |
| Ultrasound: CPP crystal deposition in fibro- or hyaline cartilage | 3 | 3 | 3 | 3 | -- | -- | -- | 3 |
| Ultrasound: CPP crystal deposition in synovial membrane/capsule/tendons | 2 | 2 | 2 | 3 | -- | -- | -- | -- |
| Cartilage calcium aggregates in the affected joint on ultrashort echo time (UTE) or in 3D dual echo steady-state gradient-echo MRI sequences | 2 | 1 | 2 | 3 | 3 | 3 | 2 | 2 |
| Dual-energy CT: CPP crystal deposition in fibro- or hyaline cartilage | 3 | 3 | 3 | 3 | 3 | -- | 3 | 3 |
| Dual-energy CT: CPP crystal deposition in synovial membrane/capsule/tendon | 3 | 3 | 3 | 3 | 3 | -- | 3 | -- |
The mode rating score is presented for each imaging modality and location
+
Imaging data from one affected joint, the knee (regardless of symptoms), and the wrist (regardless of symptoms) were ultimately recommended as candidate criteria by the Steering Committee
*
Regardless of symptoms at this joint
**
Plain radiograph of the affected joint and plain radiograph of the knee with calcification of the synovial membrane/capsule/tendon were retained per Steering Committee discussion