Table 1.
Different properties of filtered exo-proteome and secretome of the M. tuberculosis helped in identify potential candidates for epitope mapping.
| Protein Accession | Localization | Adhesion Probability | Trans-membrane HELICES | VFDB | Antigenicity | Homology Analysis | Probiotics Analysis | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Bit Score | Sequence Identity | L. rhamnosus 47,715 | L. casei 1582 | L. johnsonii 33,959) | ||||||
| core/1445/1/Org1_Gene111 | Extracellular | 0.812 | 1 | 629 | 92% | 0.4472(Antigen) | Non Similar | Non similar | Non similar | Non similar |
| core/1852/1/Org1_Gene3213 | Extracellular | 0.305 | 0 | 95.9 | 48% | 0.5303(Antigen) | N.D | N.D | N.D | N.D |
| core/2239/1/Org1_Gene1513 | Extracellular | 0.49 | 0 | 33.1 | 32% | N.D | N.D | N.D | N.D | N.D |
| core/2346/1/Org1_Gene1193 | Extracellular | 0.749 | 1 | 32.3 | 39% | N.D | N.D | N.D | N.D | N.D |
| core/2752/1/Org1_Gene1149 | Extracellular | 0.592 | 0 | 33.9 | 27% | N.D | N.D | N.D | N.D | N.D |
| core/2768/1/Org1_Gene1723 | Extracellular | 0.654 | 1 | 35 | 28% | N.D | N.D | N.D | N.D | N.D |
| core/2813/1/Org1_Gene3233 | Extracellular | 0.752 | 0 | 35.8 | 33% | N.D | N.D | N.D | N.D | N.D |
| core/3428/1/Org1_Gene19 | Extracellular | 0.574 | 0 | 157 | 85% | 0.8036 (Antigen) | Non-Similar | Non-similar | Non-similar | Non-similar |
| core/3438/2/Org2_Gene1116 | Extracellular | 0.701 | 0 | 82.4 | 57% | N.D | N.D | N.D | N.D | N.D |
| core/1269/3/Org3_Gene2358 | Extracellular | 0.886 | 0 | 31.6 | 23% | N.D | N.D | N.D | N.D | N.D |
| core/13/4/Org4_Gene3837 | Extracellular | 0.924 | 0 | 89 | 42 | N.D | N.D | N.D | N.D | N.D |
| core/293/33/Org33_Gene3334 | Extracellular | 0.798 | 0 | 51.2 | 46% | N.D | N.D | N.D | N.D | N.D |
| core/13/52/Org52_Gene3827 | Extracellular | 0.89 | 0 | 89 | 42% | N.D | N.D | N.D | N.D | N.D |
If a protein fails in one of the given analysis that protein was not forwarded to the next analysis.
N.D not done.